ProCell Microchanneling vs. MesoPen: Choosing the Best Skin Rejuvenation Treatment
When it comes to advanced skin rejuvenation treatments, ProCell Microchanneling and MesoPen microneedling are two leading options. While both treatments aim to boost collagen production, improve skin texture, and address fine lines and wrinkles, they differ in technology, effectiveness, and overall patient experience. Understanding these differences will help you choose the best option for your skincare needs.
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What Is ProCell Microchanneling?
ProCell Microchanneling is an innovative, non-invasive treatment that uses a stamping device to create controlled micro-injuries in the skin. These microchannels stimulate the body’s natural healing process, boosting collagen and elastin production. What sets ProCell apart is its use of advanced growth-factor serums, which enhance the treatment’s effectiveness by deeply penetrating the skin and accelerating cellular regeneration. (Ann Dermatol. 2014).
What Is MesoPen Microneedling?
MesoPen is a microneedling device that uses a motorized pen equipped with fine needles to create micro-injuries in the skin. Unlike traditional dermarollers, MesoPen provides adjustable needle depth for customized treatments. It improves skin tone, reduces scars, and enhances serum absorption, though it can cause more inflammation and downtime compared to microchanneling (Mesopen Pro, 2025).
Key Differences Between ProCell Microchanneling and MesoPen Microneedling
While Procell Microchanneling and MesoPen Pro Microneedling have similar goals for treating the skin, they both have varied procedure, outcome, and complications. Some of the most important differences can be broken down into a handful of categories:
| Device Feature | ProCell MicroChanneling | MesoPen Microneedling |
|---|---|---|
| Technology | Stamping device | Motorized pen |
| Skin Trauma | Minimal, precise | More inflammation due to dragging motion |
| Serum Delivery | Uses stem-cell derived growth factors | Standard serums with limited absorption |
| Healing Time | Faster due to reduced inflammation | Longer downtime due to skin irritation |
| Effectiveness | Deep collagen stimulation with serums | Good for general resurfacing, but may require more sessions |
Which Treatment Is Right for You?
- If you want maximum collagen stimulation with minimal downtime, ProCell Microchanneling is the better option.
- If you prefer a more traditional microneedling approach and are comfortable with longer healing times, MesoPen can be effective.
Why ProCell Microchanneling Is the Superior Choice
The stamping motion used in Procell treatments eliminates any chance of cuts and excessive wounding not seen by the eye that can increase downtime and the chances of complications like scaring, hyperpigmentation, and infections.
While the gliding motion used in MesoPen induces collagen production and creates sufficient depth, the vertical entry with Procell Therapies’ application of the needles covers more area with less issues.
1. Less Trauma, Faster Recovery
The stamping technique minimizes unnecessary damage, reducing redness and downtime. Depending on intensity, most Procell patients will leave slightly pink skin.
2. Advanced Growth Factor Serums
ProCell’s serums are rich in stem-cell-derived growth factors. The science behind it all: to feed and accelerate the natural healing process created by microchanneling. These growth factors support the DNA of our new cells, creating more collagen and accelerating healing.
3. More Consistent Results
Unlike microneedling, which can cause uneven penetration, microchanneling ensures uniform treatment. Similar treatments that incorporate gliding motions can cause more damage than benefit, especially when done incorrectly.
4. Better for Sensitive Skin
With customized serum delivery and a variety of pin depth/widths, patients typically experiance less irritation. ProCell is ideal for all skin types.
Experience ProCell Microchanneling at Med Aesthetics in Tustin, CA
At Med Aesthetics in Tustin, CA, we offer ProCell Microchanneling to help you achieve smoother, firmer, and younger-looking skin. Our expert team customizes each treatment to meet your unique skincare goals.
If you’re unsure whether or not out services are for you, you can check our more about microchanneling here on our website or Contact us today to schedule a consultation and experience the ProCell difference!
Related: Microchanneling vs. Microneedling: Understanding the Difference and the Benefits of Microchanneling
Sources:
- Lee HJ, Lee EG, Kang S, Sung JH, Chung HM, Kim DH. Efficacy of Microneedling Plus Human Stem Cell Conditioned Medium for Skin Rejuvenation: A Randomized, Controlled, Blinded Split-Face Study. Ann Dermatol. 2014 Oct;26(5):584-591. https://doi.org/10.5021/ad.2014.26.5.584
- Mesopen Pro. (n.d.). Why choose Mesopen Pro? Retrieved April 4, 2025, from https://www.mesopenpro.com.au/why-mesopen-pro